Prospective, early, intensified controls of retinal thickness by optical coherence tomography to detect early recurrence of disease after treatment of degenerative and proliferative retinal diseases by intravitreal injection therapy

Prospective, early, intensified controls of retinal thickness by optical coherence tomography to detect early recurrence of disease after treatment of degenerative and proliferative retinal diseases by intravitreal injection therapy - OCT-EIFU 2 - OCT-Early intensified follow-up 2

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00011705

Enrollment

100

Registered

2017-03-09

Start date

2017-03-23

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H35.3

Interventions

Group 1: All patients received three additional OCT examinations (optical coherence tomography) by protocol - in Detail: an examination of both eyes on day 14 (+/- 3 days) , day 21 (+/- 3), day 28 (+/

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with indications for treatment of degenerative or proliferative maculopathy at the Centre for Ophthalmology , which also carry out the follow-up for recurrence detection at the site as well as willingness and consent to participate in the study

Exclusion criteria

Exclusion criteria: Physical or mental conditions which make the investigation for the patient appear unreasonable ( for example, severe dementia , severe immobility , limitation of movement in the cervical spine )

Design outcomes

Primary

Measure	Time frame
Measurement of retinal thickness with optical coherence tomography (OCT) in micrometers on day 14, 21, 28 and 42 after intravitreal injection	—

Secondary

Measure	Time frame
Identification of recurring CNV activity as identification of early recurrences by signs of activity in the OCT (subretinal fluid, intraretinal edema)	—

Countries

Germany

Contacts

Public ContactPhilip Enders

Zentrum für AugenheilkundeUniklinik Köln

philip.enders@uk-koeln.de0221-48-4308

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026