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Conditions
Interventions
Group 1: Treatment group 1: Exercise intervention
Aerobic exercise of moderate-to-vigorous intensity three days a week plus muscle-strengthening exercises two days a week during 10 weeks in total. Add
Sponsors
Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters, Universitätsklinikum Frankfurt am Main
Eligibility
Sex/Gender
All
Age
14 Years to 45 Years
Inclusion criteria
Inclusion criteria: Diagnosis of ADHD according to DSM-5 criteria Stable treatment as usual comprising pharmacotherapy, group based or individual cognitive behavioural therapy (not including elements of bright light therapy or exercise)
Exclusion criteria
Exclusion criteria: IQ below 75 Any severe (comorbid) psychiatric disorder with necessary additional psychopharmaco- or day-care/inpatient therapy beyond treatment of usual Severe medical/ neurological condition not allowing bright light therapy or exercise History of epilepsy Use of antipsychotics, anti-epileptic or photosensitising medication Substance abuse/ dependency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the Inventory of Depressive Symptomatology (IDS-C30) total score (observer-blinded assessment) between baseline and end of intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Parameters assessed at baseline, at the end of the interventions, and at 12 weeks follow-up: - Clinician-rated ADHD symptoms (ADHD Rating Scales for adults and children) - Self-reported severity of depressive symptoms (Beck Depression Inventory II) - Self-reported health status and health related quality of life (Health Questionnaire EQ-5D-3L, General Health Questionnaire) - Self-reported emotional and behavioural problems (Youth self-report, Adult self-report) - Circadian rhythm (Munique Chronotype Questionnaire) - Neurocognitive functions (Cognitive Emotion Regulation Questionnaire, Rey Auditory Verbal Learning Test, Digit span) - Physical fitness (International Fitness Scale, fitness tests) - Body composition parameters - Heart rate and blood pressure - Clinician rated depressive symptoms (Inventory of Depressive Symptomatology, observer-blinded assessment, based on interview) between baseline and 12 weeks follow-up Parameters assessed at baseline and at the end of the interventions: - Short Form Health Questionnaire - Parameters measured with the mobile Health app: number of steps, movement acceleration, sleep time, context, mood regulation, reward/ stress reactivity, inattention - Concentrations of hormones - Additional neuroimaging study: Striatal fMRI signal related to reward processing | — |
Countries
Germany, Netherlands, Spain, United Kingdom
Contacts
Public ContactJutta Mayer
Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters, Universitätsklinikum Frankfurt am Main
Outcome results
None listed