Influence of genetic variants on the outcome of critically ill patients

Influence of genetic variants on the outcome of critically ill patients - Genetic variants in ICU patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00011661

Enrollment

500

Registered

2017-03-09

Start date

2010-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A41.9 J80.0

Interventions

Group 1: Critically ill patients treated on an ICU with /without Sepsis or acute respiratory distress syndrome shall be included in this study.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ICU therapy, mechanical ventilation

Exclusion criteria

Exclusion criteria: mental disorder, immunosuppression

Design outcomes

Primary

Measure	Time frame
Aim of this study is to analyze the 30 day mortality depending on genetic variants in ICU patients. Patients are enrolled in this study when first diagnosing Sepsis /ARDS or when they are admitted to ICU. Patients who are alive on day 30 are considered "survivors". In patients who die, the day after study enclosure is documented.	—

Secondary

Measure	Time frame
Disease severity as defined by ICU scores, like the simplified acute physiology score II (SAPS II).	—

Countries

Germany

Contacts

Public ContactSimon Schäfer

Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen

simon.schaefer@med.uni-muenchen.de+49 201 72384436

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026