Individually tailored E-health interventions for primary care patients with problematic alcohol use and co-occurring depressive symptoms: Phase IIa - proof of concept study

Individually tailored E-health interventions for primary care patients with problematic alcohol use and co-occurring depressive symptoms: Phase IIa - proof of concept study - ITE (Phase 2)

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011635

Enrollment

120

Registered

2017-01-20

Start date

2017-01-30

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

At-risk alcohol consumption (average daily intake of alcohol > 12g for women / >24gmen or >= one occasion a month with >= 4 alcoholic drinks for women / >= 5 drinks for men).At-risk alcohol consumption is considered as a risk factor for Harmful Alcohol use (ICD-10F10.1), Alcohol Dependence Syndrome (ICD-10 F10.2), and other alcohol attributable disease. subsyndromal depressive symptoms, majordepression (ICD-10 F32) or dysthymia (ICD-10 F34.1) F10.1: Harmful use of alcohol F10.2: Alcohol dependen

Interventions

Group 1: Participants will receive computer-based individually tailored personalized motivational feedback across different communication channels (e.g. print, e-mail, SMS, Internet) over a period of

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1) At-risk alcohol consumption (average daily alcohol use of >12g women / 24g men or >= one occasion a month with >= 4 alcoholic drinks for women / >= 5 drinks for men) 2) subsyndromal depressive symptoms, major depression or dysthymia in the past 12 months.

Exclusion criteria

Exclusion criteria: 1. Severe episode of major depression within the past 12 month and depressive symptoms in the past 2 weeks; 2. Moderate/severe alcohol use disorder according to DSM-5; 3. Illiteracy, cognitive impairment; 4. Acute or severe illness, which did not allow participation in the study; 5. less than weekly use of the Internet and no accessibility by cell phone.

Design outcomes

Primary

Measure	Time frame
A sensitive surrogate marker related to drinking behavior change will be analyzed to test potential intervention efficacy. The marker will be a latent composite measure including 1) Frequency of heavy alcohol drinking days, 2) average alcohol intake on drinking days, 3) frequency of drinking days, 4) Intention to change drinking behavior	—

Secondary

Measure	Time frame
1) Occurrence of depressive episodes, 2) Severity of depressiveness in the worst episode, 3) depressiveness at time of follow-up assessment, 4) frequency of use of depression preventive strategies	—

Countries

Germany

Contacts

Public ContactChristian Meyer

Universitätsmedizin GreifswaldInstitut für Sozialmedizin und Prävention

chmeyer@uni-greifswald.de03834/867723

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026