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Investigation of the influence of transcutaneous spinal direct current stimulation (tsDCS) on the functional connectivity of the somatosensory circuits via functional fMRI.

Investigation of the influence of transcutaneous spinal direct current stimulation (tsDCS) on the functional connectivity of the somatosensory circuits via functional fMRI.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00011606
Enrollment
20
Registered
2017-02-03
Start date
2013-01-03
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain healthy controls

Interventions

Group 1: transcutaneous-spinal direct current stimulation on thoracic spine for 20min (ANODAL) Group 2: transcutaneous-spinal direct current stimulation on thoracic spine for 20min (CATHODAL) Group 3:

Sponsors

Klinik für Anästhesiologie, Intensiv-, Palliativ- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: >18 years and <45 years voluntariness male healthy right-handed written informed consent sufficient German language skills

Exclusion criteria

Exclusion criteria: female gender left-handed, two-handed any intake of medication neurological symptoms psychiatric disorder tattoo diabetes mellitus or polyneuropathy withdrawal of declaration of consent staff of principal investigator

Design outcomes

Primary

MeasureTime frame
Changes (post-pre differences) in resting state functional connectivity within anodal and/or cathodal stimulation sessions were compared to changes in connectivity within the sham stimulation session. We hypothesize that tsDCS-induced changes in neurophysiological measures might be reflected in spontaneous brain activity in the associated networks using fMRI. Design: fMRI - tsDCS for 20min - fMRI

Secondary

MeasureTime frame
We investigated tsDCS-induced changes in somatosensory cortical connectivity by using seed-to-voxel-based analyses from the primary somatosensory cortex and the thalamus (e.g. pain circuits) prior and after 20min tsDCS visualized by fMRI.

Countries

Germany

Contacts

Public ContactChristine Meyer-Frießem

Klinik für Anästhesiologie, Intensiv-, Palliativ- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum

meyer-friessem@ains-bergmannsheil.de00492343023685

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026