chronic postsurgical pain
Conditions
Interventions
Group 1: Patients with need for surgery after fractures of arms, legs or spine. After written informed consent included patients will be assessed preoperatively and directly posteropative, 3 months an
Sponsors
Klinik für Anästhesiologie, Intensiv-, Palliativ- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: adult patients (males and females), preoperative written consent for oberservational study and analysis of blood samples, surgery after fracture of upper/ lower extremeties or spine, ability to fully understand nature and puposte of study, ability to meet the study requirements
Exclusion criteria
Exclusion criteria: < 18 years, insufficient knowledge of German language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incicende of chronic postsurgical pain following surgical treated bone fractures (upper/ lower extremities and spine) after 3 and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of CPSP in dependence of type of fracture and type of surgery; incidence of CPSP in dependence of anaesthetic procedures (general anaesthesia or peripheral nerve block or combination of both); assessment of acute posteroperative pain on numerical rating scale (NRS); postoperative presence of PPSB and components of neuropathic pain after 3 and 12 months; influence of pain on daily life activities and quality of life 3 and 12 months later; courses of immunological parameters over 3 and 12 months and their correlation with the presence of neuropathic pain | — |
Countries
Germany
Contacts
Public ContactChristine Meyer-Frießem
Klinik für Anästhesiologie, Intensiv-, Palliativ- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum
Outcome results
None listed