B23.8
Conditions
Interventions
Group 1: HIV-infected patients prepare for a marathon run over a period of 1 year. Participants train three to four times per week following individual training plans provided (3 to 4 hours per week a
Sponsors
Universitätsklinikum BonnMedizinische Klinik I
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - HIV-infection - certificate of the treating HIV-specialist that participation in marathon and lactacte stress test is possible - signed informed consent form before inclusion
Exclusion criteria
Exclusion criteria: - younger than 18 years - missing health certificate - obvious reason not to participate in Marathon running - new AIDS-defining event = 1 months before inclusion - malignant disease with current chemotherapy - organ transplant - Treatment with systemic corticosteroids = 3 months before inclusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD4 cell count, viral load 12, 9, and 6 months and right before the marathon run. Number and severity of infections during the whole observation period and 4 weeks afterwards. | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolic Parameters (lipids, glucose), safety Parameters (liver transaminases, creatinkinase, Phosphate), immunologic Parameters (CD4T-cell apoptosis), oxidative stress and antioxidative capacity (with photometric analysis of capillary blood); quality of life with Medical Outcomes Study HIV Health Survey (MOS-HIV) 12, 9, and 6 months and right before the marathon run | — |
Countries
Germany
Contacts
Public ContactMartin Vogel
Universitätsklinikum Bonn
Outcome results
None listed