Characterization of the Sensitization Spectrum towards frequent and rare inhalation allergens in patients with severe asthma with special emphasis on regional differences

Characterization of the Sensitization Spectrum towards frequent and rare inhalation allergens in patients with severe asthma with special emphasis on regional differences - ATLAS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00011586

Enrollment

1500

Registered

2017-01-16

Start date

2017-04-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J45.0 J45.1 J45.8

Interventions

Group 1: - approx. 500 Pulmonary surgeons who are located throughout Germany are to be won over for the project - from patients with severe asthma who are diagnosed with allergological diagnostics, a

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18-80 years 2. Sex: male and female 3. no restriction on body weight 4. Indication: severe asthma bronchiale (definition according to ERS = European Thoracic SocietyATS=American Thoracic Society), GINA (Global Initiative for Asthma) stages 4-5 5. Declaration of consent by signed informed consent

Exclusion criteria

Exclusion criteria: 1. Chronic obstructive bronchitis (COPD) 2. Collagonia, autoimmune diseases 3. Lack of written consent or approval

Design outcomes

Primary

Measure	Time frame
Characterization of the sensitization spectrum against frequent and rare inhalation allergens on a representative sample of 1500 patients with severe bronchial asthma	—

Secondary

Measure	Time frame
- Differences in regional sensitization - Dependence of eosinophilia on IgE-mediated sensitization - Verifying the hypothesis that in patients with severe hypereosinophilic asthma, there is often no evidence of allergy	—

Countries

Germany

Contacts

Public ContactJens Schreiber

Universitätsklinik für Pneumologie

jens.schreiber@med.ovgu.de+49-391-67-15421

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026