Manual body acupuncture and self-administered hydrotherapy in the treatment of chronic, chemotherapy-induced peripheral neuropathy - a randomized controlled trial

Manual body acupuncture and self-administered hydrotherapy in the treatment of chronic, chemotherapy-induced peripheral neuropathy - a randomized controlled trial - Acu-PeriPol

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011525

Enrollment

Registered

2017-01-02

Start date

2013-03-27

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G62.8

Interventions

Group 1: 12 manual acupuncture session (2x/week for 6 weeks) following a semi-standardized protocol Group 2: self-administered cold water appplications on legs or arms as required (for six weeks)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - > 3 months of chemotherapy induced peripheral polyneuropathy (at least WHO grade II) - completed chemotherapy - sufficient knowledge of the German language - written informed consent

Exclusion criteria

Exclusion criteria: - severe mental or physical disease that prevent study participation - pregnancy - systemic-neurological diseases (multiple sclerosis, parkinson, dementia) - tumour-associated neuropathy or other causes of neuropathic pain (diabetes, radicular symptoms, alcohol/drug abuse) - other acupuncture treatment during study phase

Design outcomes

Primary

Measure	Time frame
change in subjective evaluation of symptoms (VAS) after 6 weeks with additional acupuncture or hydrotherapy (T1-T0)	—

Secondary

Measure	Time frame
change in subjective evaluation of quality of life (symtom diary, standardized questionnaires) change in somatosensory thresholds (QST parameter) daily functional restrictions (standardized questionaires) use of medication (diary) The symptom diary and the use of medication are protocolled during baseline and the whole therapy period. All other questionnaires and measurements are taken before the first therapy onset, after 6 weeks before the change of therapry, and after 3 months after baseline.	—

Measure

Time frame

change in subjective evaluation of quality of life (symtom diary, standardized questionnaires) change in somatosensory thresholds (QST parameter) daily functional restrictions (standardized questionaires) use of medication (diary) The symptom diary and the use of medication are protocolled during baseline and the whole therapy period. All other questionnaires and measurements are taken before the first therapy onset, after 6 weeks before the change of therapry, and after 3 months after baseline.

—

Countries

Germany

Contacts

Public ContactGustav Dobos

Universität Duisburg-Essen, Lehrstuhl und Klinik für Naturheilkunde und Integrative Medizin, Knappschafts-Krankenhaus, Kliniken Essen-Mitte

g.dobos@kliniken-essen-mitte.de0049-(0)201 174 25001

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026