Brain-computer interface and neuromuscular stimulation for rehabilitation following sub-acute stroke

Brain-computer interface and neuromuscular stimulation for rehabilitation following sub-acute stroke - BCI-NMES-CVA

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011522

Enrollment

Registered

2017-02-21

Start date

2016-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I61 I63

Interventions

Group 1: Test group (20 participants): the arm musculature will be stimulated at the timepoint at which the patient attempts to move, determined from the EEG. Group 2: Control group (20 participants):

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - First stroke (thrombotic or haemorrhagic), diagnosed with CT or MRI, lasting 4 weeks to 6 months - Reduced or absent power of the affected extremity (arm/hand)

Exclusion criteria

Exclusion criteria: - sever aphasia - Medical Research Council Power Test: >= 3 - cognitive impairment leading to inability to perform the tasks: Montreal Cognitive Assessment (> 25) - severe depression - medically unstable (postural hypotension, sepsis, epilepsy, severe renal failure, hemispatial neglect, severe visual impairment, fixed joint contractures, skin condition which could be worsened by electrode placement) - certain medications (L-dopa, amantadine. Antidepressive medication is permissible.) - history of epilepsy - Fatigue Severity Scale: > 36/63 - Pain Scale: > 5/10

Design outcomes

Primary

Measure	Time frame
Improvement of mobility, to enable performance of daily tasks. To be evaluated and quantified using the Fugl-Mayr Assessment: motor arm. The test will be carried out before the therapy, at the end of each week of therapy, and 6 months after the therapie.	—

Secondary

Measure	Time frame
The following tests will be carried out before the therapy, after 3 and 5 weeks, and 6 months after the therapy: - Medical Research Council Power Test - Rivermead Test - Barthel Index - National Institute of Health Stroke Scale (motor: Arm) - European Stroke Scale - Modified Ashworth Scale (spasticity) - Sensory deficits (Since feedback is visual as well as sensory, these patients will be included. Baseline 2-point discrimination and proprioceptive tests will be performed.) - Standard clinical evaluation of the cranial and peripheral nerves, gait, Romberg test - Neuropsychological profile (with Montreal Cognitive Assessment) - Goal attainment questionnaire - Stroke Impact Scale	—

Measure

Time frame

The following tests will be carried out before the therapy, after 3 and 5 weeks, and 6 months after the therapy: - Medical Research Council Power Test - Rivermead Test - Barthel Index - National Institute of Health Stroke Scale (motor: Arm) - European Stroke Scale - Modified Ashworth Scale (spasticity) - Sensory deficits (Since feedback is visual as well as sensory, these patients will be included. Baseline 2-point discrimination and proprioceptive tests will be performed.) - Standard clinical evaluation of the cranial and peripheral nerves, gait, Romberg test - Neuropsychological profile (with Montreal Cognitive Assessment) - Goal attainment questionnaire - Stroke Impact Scale

—

Countries

Germany, Italy, Switzerland

Contacts

Public ContactCatherine Sweeney-Reed

Unversitätsklinik für Neurologie

catherine.sweeney-reed@med.ovgu.de+49-391-6117-544

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026