C00-C97 G62.0
Conditions
Interventions
Group 1: Balance training two times/week (20-30 minutes) over 12 weeks at neurotoxic chemotherapy onset
Group 2: Balance training with force platform and visual feedback two times/week (20-30 minutes)
Sponsors
Universitätsklinik und Poliklinik für Innere Medizin IV
Eligibility
Sex/Gender
All
Age
15 Years to No maximum
Inclusion criteria
Inclusion criteria: histologically confirmed tumor diagnosis (main diagnosis), therapy with platinum derivatives, taxanes or vincristine, living in Halle or in the immediate surroundings, adequate mobility and autonomy, written consent
Exclusion criteria
Exclusion criteria: no suitability for participation in the study from the medical point of view, Relevant disturbance of pallesthesia (tuning fork) / pre-existing polyneuropathy, lack of german language skills
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of patient-reported quality of life (questionnaire: EORTC-QLQ-CIPN20) between baseline (week 0, t1), end of intervention (week 12, t2) and follow-up (week 16, t3) | — |
Secondary
| Measure | Time frame |
|---|---|
| change of quality of life (EORTC-QLQ-C30), neuropathy related pain (Pain-Detect), pallesthesia (tuning fork), sensory disburtance (numbness, tingling, temperature), electrical impulses of muscles (electromyographie, MUAP), nerve conduction velocity and sympathetic skin response (electroneurography), mobility (TUGT), postural control (posturographic, IBS Tetrax), muscular proprioceptive reflex (patellar/achilles) and neuropathy scores (CTC AE 4.3, Total Neuropathy Score) between baseline (week 0, t1), end of intervention (week 12, t2) and follow-up (week 16, t3) | — |
Countries
Germany
Contacts
Public ContactAndré Golla
Universitätsklinikum Halle (Saale) Landeszentrum für Zell- und Gentherapie Onkologische Sport- und Bewegungstherapie
Outcome results
None listed