presurgical universal decolonisation in native Joint arthroplasty with polyhexanid

presurgical universal decolonisation in native Joint arthroplasty with polyhexanid - PREVENTION

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011505

Enrollment

4800

Registered

2017-02-15

Start date

2017-01-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical site infections after primary total joint arthroplasty in native hip-/ knee joints or spondylodesis. T81.4

Interventions

Group 1: Intervention Group: Universal decolonisation of patients that meet the criteria with polyhenid containing washcloths, gel for intranasal application and mouthwash. Products should be used at

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Indication for a native joint arthroplasty of the knee/ hip or a spondylodesis/surgery of the lumbar spine.

Exclusion criteria

Exclusion criteria: known allergy against polyhexanid or other substances that are present in the decolonisation products. Indication for surgery that is not a native joint arthroplasty of the knee/ hip or a spondylodesis/surgery of the lumbar spine.

Design outcomes

Primary

Measure	Time frame
Rate of surgical site infections defined in the participating Centers in the german surveillance System for nosocomial infections/ KISS (CDC-definitions).	—

Secondary

Measure	Time frame
questionnaire evaluating Patient satisfaction and safety.	—

Countries

Germany

Contacts

Public ContactTobias Kramer

Charité Universitätsmedizin BerlinInstitut für Hygiene und Umweltmedizin

prevention-studie@charite.de030/450-577 912

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 25, 2026