HYPOXIA healthy subjects
Conditions
Interventions
Group 1: The purpose of this experimental trial is to investigate the acute effects of normobaric hypoxia on acid-base parameters in humans. Therefore, 16 subjects stay for twelve hours in a hypoxic c
Sponsors
Ruhr-Universität Bochum, Institut für Sportwissenschaft, Lehrstuhl für Sportmedizin und Sporternährung
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: - moderately active lifestyle - attested full physical fitness
Exclusion criteria
Exclusion criteria: - cardial or pulmonary desease - altitude sojourn above 2000m within the last two weeks before experimental trial - acute infects - chronic medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess changes in acid-base balance, capillary blood samples are taken every hour during the blood gas parameters pH, [HCO3]-, BE and saO2. One blood gas analysis is carried out before entering the hypoxic chamber and twelve during exposure to simulated altitude. Furthermore, heart rate and oxygen saturation are measured hourly using a puloximetry. | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of eliminated urine and associate urinary pH are assessed to describe hypoxia-induced diuretic effects. To asses possible metabolic effects of nutrition on acid-base status, nutrition protocols are completed. | — |
Countries
Germany
Contacts
Public ContactMirjam Limmer
Deutsche Sporthochschule Köln, Institut für Natursport und Ökologie
Outcome results
None listed