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RAD327 Lu-177 Dosimetry with SPECT/CT

RAD327 Lu-177 Dosimetry with SPECT/CT - RAD327 COMPARE PRRT

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00011489
Enrollment
6
Registered
2017-07-19
Start date
2017-09-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neuroendocrine tumors C80 C17 C25.9

Interventions

Group 1: Therapy companion imaging is performed in patients with neuroendocrine tumors treated by Lutetium-177 DOTATATE. Organ doses were calculated using image data. Beside, the standard protocol def

Sponsors

Universitätsklinikum Magdeburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Indication for Lutetium-177-DOTATATE therapy - by minimum two successfully performed therapy cycles - age > 18 years - normal renal function - no contraindication for the second examinations (e.g. claustrophobia, poor general condition)

Exclusion criteria

Exclusion criteria: Missing compliance to the additional examinations

Design outcomes

Primary

MeasureTime frame
Comparison in detection rate of focal lesions by two different SPECT/CT-systems for (1.) scintigraphy and (2.) SPECT/CT in Lutetium-177-DOTATATE therapy

Secondary

MeasureTime frame
- Comparison of reader's confidence in image quality in whole body scintigraphy for both detector technologies - Comparison of reader's confidence in image quality and assignment to morphologic structures for SPECT(NaJ)/CT and SPECT(CZT)/CT -Comparison of uptake/nuclide accumulation in defined target regions (e.g. tumor, kidney)

Countries

Germany

Contacts

Public ContactAnja Zinke

Klinik für Radiologie und Nuklearmedizin

anja.zinke@ed.ovgu.de+49-391-6713071

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026