Status post kidney transplantation Z94.0
Conditions
Interventions
Group 1: In kidney transplantated patients showing up to our service for standard of care after kidney transplantation, sonographic elastography will be performed baseline and at 6 and 12 months and
Sponsors
Klinik für Innere Medizin 1, Universitätsklinik Ulm
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: • Kidney transplant recipients with follow up in renal outpatient clinic in Universities of Ulm and Mannheim. • Age = 18 yrs • Written informed consent for study participation
Exclusion criteria
Exclusion criteria: • Severe neurological or psychiatric disorders influencing with study consent • Missing consent for study participation • Anatomical characteristics interfering with the elastographic measurement • Contraindications for ultrasonographic testing • Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Allograft function (estimated by EKD-EPI GFR) baseline and after 3, 6, 9 and 12 months and shear wave velocity (in m/s) determined by ARFI based elastography at baseline and after 6 and 12 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Proteinuria and urinary biomarkers associated with acute and chronic kidney injury (Neutrophil-Gelatinase-Associated Lipocalin (NGAL), Clusterin, Interleukin (IL) -18, Kidney Injury Molecule (KIM) -1, complement factors C3a, C5a and terminal complement complex) (Month 0, 3, 6, 9 and 12) | — |
Countries
Germany
Contacts
Public ContactRené van Erp
Universitätsklinikum Ulm, Kliniken für Innere Medizin 1
Outcome results
None listed