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Comparison of the detection rate in SPECT/CT with NaI detectors and SPECT/CT with CZT semiconductor detectors used in bone scintigraphy - RAD324

Comparison of the detection rate in SPECT/CT with NaI detectors and SPECT/CT with CZT semiconductor detectors used in bone scintigraphy - RAD324 - COMPARE Bone - RAD324

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00011421
Enrollment
48
Registered
2017-01-20
Start date
2017-01-25
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone metastases C79.5

Interventions

Group 1: In total 48 patients will be enrolled in the study. For these patients bone metabolism is examined by two competitive hybrid systems (SPECT/CTs). The system used for the clinically indicated

Sponsors

Universitätsklinikum Magdeburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Presence of an indication for bone scintigraphy in malignancy • Patient age > 18 years • normal renal function • No contraindications for a second examination sequence (e.g., claustrophobia, poor general state)

Exclusion criteria

Exclusion criteria: • no compliance for the second examination • Suspected of benign bone disease

Design outcomes

Primary

MeasureTime frame
Non-inferiority of a detector technology: Comparing the detection rates of pathological bone metabolism between two different SPECT/CT systems used in imaging of bone metabolism by (1) planar whole body imaging and (2) SPECT/CT.

Secondary

MeasureTime frame
(1.) Comparison of readers confidence in whole body image quality (2.) Comparison of readers confidence in SPECT/CT image quality and alignment of morphologic structures

Countries

Germany

Contacts

Public ContactAnja Zinke

Klinik für Radiologie und Nuklearmedizin

anja.zinke@ed.ovgu.de+49-391-6713071

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026