Effects of transcranial gamma alternating current stimulation (ytACS) in patients with schizophrenia, depression, and in healthy controls

Effects of transcranial gamma alternating current stimulation (ytACS) in patients with schizophrenia, depression, and in healthy controls - ytACS cognition

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011364

Enrollment

168

Registered

2016-11-23

Start date

2016-12-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F20.0 F32 F33

Interventions

Group 1: Baseline: cognitive test battery with Attention Network Test, n-back-test, trail making test, d2 test, VLMT. Intervention: single active ytACS (40 Hz, -1 to +1 mA, range 2 mA, 48000 cycles, i

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Diagnosis of schizophrenia or depression, both with stable medication; no psychiatric diagnosis for healthy controls

Exclusion criteria

Exclusion criteria: pregnancy, lactation, metal implants in the head (except teeth)

Design outcomes

Primary

Measure	Time frame
Improvement in cognition after one active stimulation compared to sham stimulation in trail making test, TMT; D2 test; verbal learning and memory test, VLMT; n-back-test; Regensburg word fluency test, RWT	—

Secondary

Measure	Time frame
profile of side effects of ytACS, shown by the Comfort Rating Questionnaire (CRQ) between active and sham stimulation	—

Countries

Germany

Contacts

Public ContactUlrich Palm

Psychiatrische Klinik

ulrich.palm@med.uni-muenchen.de089/4400-55881

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026