reduce of facial skin elasticity in healthy volunteers
Conditions
Interventions
Group 1: Micropuncture injections of 5 ml autologous conditioned serum (ACS) in the face in week 0, 4, 8 and facultative in week 12.
Group 2: Micropuncture injections of 5 ml autologous conditioned s
Sponsors
Universität Hamburg Fachrichtung Kosmetikwissenschaft
Eligibility
Sex/Gender
Female
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Provision of signed and dated informed consent form to participate in the study 2. Non-pregnant female aged 35-65 years 3. High loss of facial skin elasticity according to the Investigator’s opinion
Exclusion criteria
Exclusion criteria: 1. Severe skin diseases e.g. psoriasis, atopic eczema (neurodermatitis) or other autoimmune skin diseases 2. Skin cancer in the anamnesis 3. Systemic diseases with skin involvement (SLE) 4. Pre-treatment with laser, botox or hyaluronic acid in the tested face area (treatment areal) 5. Severe diet in the last 3 months or nutritional supplementary during the last 3 years 6. Acute infection 7. Chronic acne
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gain in skin elasticity measured between baseline and week 12 with the Cutometer dual MPA 580 (Courage Khazaka electronic GmbH, Colonge). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Intraindividual difference between baseline and week 12 on the „Global Aesthetic Improvement Scale“ (GAIS). 2. Intraindividual difference between baseline and week 12 of the patients’ attractivity self-assessment on a 7 point scale 3. Intraindividual difference between baseline and week 12 on the „Facial Appearance Self-Perception Questionnaire" (FASPQ). | — |
Countries
Germany
Contacts
Public ContactMartina Kerscher
Universität Hamburg Fachrichtung Kosmetikwissenschaft
Outcome results
None listed