Interaction of coagulation FACtors, Thrombocytes and leukOcytes in patients with aRterial hypeRtension study

Interaction of coagulation FACtors, Thrombocytes and leukOcytes in patients with aRterial hypeRtension study - FACTO-RR study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00011232

Enrollment

Registered

2016-11-04

Start date

2014-08-20

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I10

Interventions

Group 1: Controlled hypertension Directly after study enrolment, Medical history was taken and body weight, height and heart rate were obtained. Office blood pressure was measured in each study partic

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: essential arterial hypertension

Exclusion criteria

Exclusion criteria: Age =90 years, anticoagulant therapy (unfractionated or low molecular weight heparin, vitamin K antagonist, FXa-inhibitors, thrombin inhibitors), acute coronary syndromes, exacerbated disease requiring critical care medicine (e.g. hypertensive crisis with pulmonary edema and respiratory failure) or immediate surgery (e.g., aortic dissection or rupture).

Design outcomes

Primary

Measure	Time frame
Correlation of the severity of arterial hypertension with markers of activation of the coagulation system as well as thrombocyte and leukocyte (patho)physiology. Medical history was taken and body weight, height and heart rate were obtained. Office blood pressure was measured in each study participant in an upright sitting position (room temperature 22° centigrade) using the Omron 705CP-II (Omron) device and upper arm cuffs adapted to upper arm circumference (17-22 cm, 22-32 cm an 32-42 cm, respectively). Immediately after that, a maximum of 10ml of venous citrated blood was drawn from the cubital vein of the right arm to prepare platelet rich and platelet poor plasma, leukocyte preparations and to assess blood count.	—

Measure

Time frame

Correlation of the severity of arterial hypertension with markers of activation of the coagulation system as well as thrombocyte and leukocyte (patho)physiology. Medical history was taken and body weight, height and heart rate were obtained. Office blood pressure was measured in each study participant in an upright sitting position (room temperature 22° centigrade) using the Omron 705CP-II (Omron) device and upper arm cuffs adapted to upper arm circumference (17-22 cm, 22-32 cm an 32-42 cm, respectively). Immediately after that, a maximum of 10ml of venous citrated blood was drawn from the cubital vein of the right arm to prepare platelet rich and platelet poor plasma, leukocyte preparations and to assess blood count.

—

Countries

Germany

Contacts

Public ContactPhilip Wenzel

Universitätsmedizin Mainz, Zentrum für Kardiologie - Kardiologie I

wenzelp@uni-mainz.de06131177695

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026