Investigation of reward anticipation and delay discounting in ADHD and comorbid disorders via fMRI - substudy 1: a pharmaco-fMRI study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011209

Enrollment

Registered

2016-11-11

Start date

2016-11-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Group 1: fmri placebo (crossover) during the test paradigms "reward anticipation" and "delay discounting" Group 2: L-DOPA (crossover) during the test paradigms "reward anticipation" and "delay discoun

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: german language, healthy volunteers

Exclusion criteria

Exclusion criteria: severe acute or chronic disorder, medication intake, pregnancy, mri exclusion criteria

Design outcomes

Primary

Measure	Time frame
striatal BOLD-fMRI-signal one hour after study drug intake	—

Secondary

Measure	Time frame
behavioral measures of Paradigms according to McClure et al 2003 and Knutsonet al 2003 via presentation software (money won, reaction time and decision type early vs. late)	—

Countries

Germany

Contacts

Public ContactOliver Grimm

Klinik für Psychiatrie

oliver.grimm@kgu.de069 6301 4784

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026