G20.9
Conditions
Interventions
Testing for abnormal central pain processing
Group 1: Patients with Parkinson's disease and pain
We want to compare the patients and contol persons by using laser evoked potentials. These potentials will be created at the location of the main pain of the patients.
We are searching for different
Testing for abnormal central pain processing
Group 3: age - matched normal persons
Sponsors
Universitätsklinikum Schleswig-Holstein Campus Kiel
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) legal competence of the study participants (MOCA > 18), signed informed consent 2) ability to adequate communication and editing of the used questionnaires 3) a) clinical signs of Parkinson's disease at stadium Hoehn and Yahr 2 - 3 b) abnormal sniffing sticks test c) hyperechoic substantia nigra at transcranial ultrasonic examination at least at one side (with sufficient ultrasound window); in addition no sign of a secondary or atypical parkinson syndrome 4) in the painful group no other explanation for the occurence of pain is found
Exclusion criteria
Exclusion criteria: 1) abuse of alcohol, illegal drugs or medicine in the past (or suspect of the tester) 2) known other neurologic disease, which leads to different sensoric sensation 3) pregnancy and lactation period 4) members of family of the testers 5) membership in an other study for the last four weeks befor the recruitment visit 6) therapy with strong analgesics (WHO -3)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main aim of this study is the detection of abnormal central pain processing in patients with Parkinson's disease | — |
Secondary
| Measure | Time frame |
|---|---|
| Differentiation between painful and painless PD syndromes regarding central pain processing | — |
Countries
Germany
Contacts
Public ContactPhilipp Hüllemann
Klinik für Neurologie, Universitätsklinikum Schleswig-Holstein Campus Kiel
Outcome results
None listed