Remote ischemic preconditioning in patients with aneurysmal subarachnoid hemorrhage

Remote ischemic preconditioning in patients with aneurysmal subarachnoid hemorrhage - RIP_SAH

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00011177

Enrollment

Registered

2019-09-09

Start date

2019-11-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I60.7 I63.9

Interventions

Group 1: Participants will be randomised 1:1 to either the intervention (preconditioning) group or the control (sham) group. In both RIPC and SPC, a standard blood pressure cuff is fixed on the patien

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - patients suffering from aneurysmal subarachnoidal bleeding - written consent for study participation by patient, family member or by an independent physician in case of inability to consent - age > 18 years

Exclusion criteria

Exclusion criteria: - peripheral arterial disease - time after hemorrhage >48 hours - diabetes mellitus and intake of oral antidiabetic medication - inability to consent - pregnancy - age< 18 years

Design outcomes

Primary

Measure	Time frame
Volumetry of ischemic area con cranial CT scan 2 to 3 weeks post subarachnoid hemorrhage	—

Secondary

Measure	Time frame
Secondary outcome is the severity of neurological impairment, which will be scored by the National Institutes of Health Stroke Scale (NIHSS) at time at admission to the hospital, 1 and 2 weeks, 3 months and 1 year after bleeding and by the Modified Rankin Scale (mRS) at discharge, 3 months and 1 year after bleeding. Furthermore, doppler studies will be conducted daily for the detection of vasospasm.	—

Measure

Time frame

Secondary outcome is the severity of neurological impairment, which will be scored by the National Institutes of Health Stroke Scale (NIHSS) at time at admission to the hospital, 1 and 2 weeks, 3 months and 1 year after bleeding and by the Modified Rankin Scale (mRS) at discharge, 3 months and 1 year after bleeding. Furthermore, doppler studies will be conducted daily for the detection of vasospasm.

—

Countries

Germany

Contacts

Public ContactJens Gempt

Neurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar

jens.gempt@tum.de08941409722

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026