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Cramp threshold increase by capsaicin? Efficiency of different dosage forms

Cramp threshold increase by capsaicin? Efficiency of different dosage forms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00011132
Enrollment
24
Registered
2016-09-28
Start date
2016-09-29
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects R25.2

Interventions

Group 1: Pre-measurement Cramp Threshold Frequency. The biphasic stimulation pattern (5s on 55s off) is performed by Stim Pro X9 at 40mA and a rectangular pulse width of 150µs. The CTF-determination s

Sponsors

Institut für Trainingswissenschaft und Sportinformatik
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: men between 18 and 50 years

Exclusion criteria

Exclusion criteria: Injuries of the musculoskeletal system of the lower extremity in the last six months prior to the study and cardiopulmonary basic diseases and hypersensitivity to spicy food.

Design outcomes

Primary

MeasureTime frame
The time endpoint of the study is the CTF measurement (Cramp Threshold Frequency) 3 hours after the nasal spray application. At each times after this application the change of the CTF of the calf muscles by EMG and EMS will be checked. Before application of the spray and 15 minutes, 1.5 and 3 hours after, the CTF-determination for measuring the minimum pacing rate, which triggers a spasm in the medial gastrocnemius muscle will be measured.

Countries

Germany

Contacts

Public ContactMichael Behringer

Institut für Trainingswissenschaft und Sportinformatik

behringer@dshs-koeln.de+49(0)221 4982 3620

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026