Z94.4
Conditions
Interventions
Group 1: We will enroll 30 patients, undergoing a liver transplantation, during the investigation period at the university hospital heidelberg. In this context, the gastrointestinal microbiome shall b
T10 (tenth day after surgery)
T90 (sample of day 90 after surgery).
Sponsors
Klinik für AnaesthesiologieUniversitätsklinikum Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: all patients getting a liver transplantation at the university medical center during the period of research are being implemented if declaration of agreement is present
Exclusion criteria
Exclusion criteria: missing fulfillment of inclusion criteria, pregnancy, HIV positive, denial of participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Following points are being researched as a main criteria in patients after liver transplantation performed at a german university medical center: Sequencing of donor’s as well as graft receiving patient’s gastrointestinal microbiome via 16s RNA analysis. To work out changes in receiving patient’s microbiome via 16S RNA analysis as a consequence of immunosuppressive therapy Stool samples will be collected at following days: Before surgery (during consultation hour); T1 (first day after surgery); T3 (third day after surgery); T5 (fifth day after surgery); T10 (tenth day after surgery); T90 (sample of day 90 after surgery). | — |
Secondary
| Measure | Time frame |
|---|---|
| evaluation of possible connection between gastrointestinal microbiome and individual outcome | — |
Countries
Germany
Contacts
Public ContactFelix Schmitt
Klinik für AnaesthesiologieUniversitätsklinikum Heidelberg
Outcome results
None listed