Prospective trial for evaluation of potential heart dose reduction using deep inspiration breath-hold in radiotherapy of left-sided breast cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00010929

Enrollment

Registered

2016-08-05

Start date

2014-11-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C50.9

Interventions

Group 1: Irradiation and Planning in deep inspiration breath-hold for left sided breast cancer patients using the sentinelTM/catalystTM surface System and automatic interconnection for beam-on/-off Si

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: left-sided breast cancer indication for adjuvant whole breast irradiation

Exclusion criteria

Exclusion criteria: informed consent not possible breath-hold of 20 seconds not possible

Design outcomes

Primary

Measure	Time frame
significant heart dose reduction in planning and Treatment checked by heart inside Treatment field and further Parameters like heart mean and max dose as well as max LAD (left anterior descending artery) dose.	—

Secondary

Measure	Time frame
lung dose assessment (mean lung dose, left lung V20Gy), target dose coverage (V95%), clinical feasability Follow-Up using Lent-Soma Criteria Follow-Up for cardiac toxicity (10-20 years) no endpoint of this study	—

Countries

Germany

Contacts

Public ContactCLaus Belka

Klinikum Großhadern Klinik für Strahlentherapie und Radioonkologie

claus.belka@med.uni-muenchen.de004989440074521

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 12, 2026