N73.6 N99.4
Conditions
Interventions
Group 1: The CD90 cell population is identified in peritoneal, adhesion, and omentum specimens from adult patients undergoing gynecologic surgery for benign gynecologic disease.
Intraoperatively, a m
Sponsors
Forschungspool der Carl - von - Ossietzky Universität Oldenburg
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Woman equal to and above 18 years of age. Woman with a negative pregnancy test at the time of recruitment Woman with any gynecological pathology requiring scheduled pelvic gynecological surgery, either laparotomy or laparoscopy. Woman without primary peritoneal disease, other than adhesions.
Exclusion criteria
Exclusion criteria: Woman with a primary peritoneal pathology. Emergency surgery Patients under systemic immunosuppressive therapy in the previous 6 months Patients with current intra-abdominal or pelvic abscess or systemic infection Pregnant woman Simultaneous participation in another clinical trail
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our primary objective will be the identification of the CD90 cellpopulation in peritoneum, adhesion and omentum by histologic expression of CD90. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondly, we want to show the stem cell like multipotency of these cells by expression of CD31 and CD71 markers. Thirdly, we want to characterize the cells’ wound healing potential through the expression of the EPO receptor and beta-cr subunit via next gen sequencing. | — |
Countries
Germany
Outcome results
None listed