The impact of endogenous testosterone for gender differences in pain, sensory perception and therapy of pain

The impact of endogenous testosterone for gender differences in pain, sensory perception and therapy of pain - TestoSense

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00010854

Enrollment

120

Registered

2017-01-03

Start date

2014-12-09

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Testosterone and sensory perception

Interventions

Group 1: Participants with assumed lack of endogenous testosterone: Testing the sensory function by standardized test battery of sensory funtion (QST) and determine endogenous inhibition dependent on

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: male sex, legal age, assumed lack of endogenous testosterone (in patient group)

Exclusion criteria

Exclusion criteria: Chronic pain condition, chronic nervous diseases, chronic psychiatric diseases, chronic analgetic use, abuse, other conditions with alterations in pain

Design outcomes

Primary

Measure	Time frame
endogenous inhibition: Conditioned-Pain-Modulation-Effect (CPM-Effect),	—

Secondary

Measure	Time frame
Variables from QST (quantitative sensory testing) protocol (Cold Detection Threshold, CDT; Warmth Detection Threshold, WDT; Thermal Sensory Limen, TSL; Paradoxal Heat Sensation, PHS; Cold Pain Threshold,CPT; Heat Pain Threshold, HPT; Mechanical Detection Threshold, MDT; Mechanical Pain Threshold, MPT; mechanical pain sensitivity, MPS; Dynamic Mechanical Allodynia, DMA Wind-Up-Ration, WUR; Vibration Detection Threshold, VDT; Pressure Pain Threshold, PPT)	—

Measure

Time frame

Variables from QST (quantitative sensory testing) protocol (Cold Detection Threshold, CDT; Warmth Detection Threshold, WDT; Thermal Sensory Limen, TSL; Paradoxal Heat Sensation, PHS; Cold Pain Threshold,CPT; Heat Pain Threshold, HPT; Mechanical Detection Threshold, MDT; Mechanical Pain Threshold, MPT; mechanical pain sensitivity, MPS; Dynamic Mechanical Allodynia, DMA Wind-Up-Ration, WUR; Vibration Detection Threshold, VDT; Pressure Pain Threshold, PPT)

—

Countries

Germany

Contacts

Public ContactVasco Deichert

Klinik für Anästhesiologie, operative Intensivmedizin und Schmerztherapie

vasco.deichert@ukmuenster.de0049-251-83-48317

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026