F20
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: informed consent, diagnosis of schizophrenia according to DSM-V, total postive and negative syndrome scale score 75 or lower, reliable contraception in women of child-bearing age
Exclusion criteria
Exclusion criteria: lack of accountability, substance abuse at screening (except benzodiazepines), serious suicidal risk at screening visit, other relevant interferences of axis 1 according to diagnostic evaluation (MINI), other relevant neurological or other medical disorders, pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WHO Disability Assessment Schedule, 36-item interview (4 time points: baseline, after 4 weeks, after 12 weeks, after 18 weeks) | — |
Secondary
| Measure | Time frame |
|---|---|
| muscle strength, isometric maximal test of 4 main muscle groups (3 timepoints: baseline, after 12 weeks, after 18 weeks) - metabolic profile, blood analysis, BMI, waist circumference, blood pressure (3 timepoints: baseline, after 12 weeks, after 18 weeks) - PANSS-score, Positive and negative syndrome scale (3 timepoints: baseline, after 12 weeks, after 18 weeks) - cognition (e.g. Verbal Learning and Memory Test, VLMT) (3 timepoints: baseline, after 12 weeks, after 18 weeks) | — |
Countries
Germany
Contacts
Klinik für Psychiatrie und Psychotherapie, Klinikum der Universität München