Does a ten days high intensity training induce DNA-damage, measured by the FADU-Assay

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00010841

Enrollment

Registered

2016-10-21

Start date

2016-09-30

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overtraining Syndrom healthy population

Interventions

Group 1: The experimental group will perform a ten days high intensity endurance training on a cycle ergometer. One session consists of 8 bouts with an intensity of 300W-370W. Recovery time is based o

Eligibility

Sex/Gender

Male

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: male, between 20 and 50 years, at least three years of training an competition experience

Exclusion criteria

Exclusion criteria: BMI > 30, cardiological symptoms, injuries or diseases with need of medication, hormone diseases (diabetes etc.)

Design outcomes

Primary

Measure	Time frame
DNA damage, measured with FADU assay ((Fluorimetric Analysis of Alkaline DNA Unwinding)) at the beginning and after ten days training period. Last measurement will be four days after training.	—

Countries

Germany

Contacts

Public ContactSascha Schlechtweg

Universität Stuttgart, Institut für Sport- und Bewegungswissenschaft, Abteilung Sportbiologie und Biomechanik

sascha.schlechtweg@inspo.uni-stuttgart.de+49 (0)711 / 685 - 68249

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026