Controlled human crossover intervention trial to demonstrate the chemopreventive potential of Ethiopian mustard (Brassica carinata) - pilot study

Controlled human crossover intervention trial to demonstrate the chemopreventive potential of Ethiopian mustard (Brassica carinata) - pilot study - BraCa study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00010836

Enrollment

Registered

2016-07-25

Start date

2016-08-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer prevention Healthy volunteers

Interventions

Group 1: Brassica carinata (Ethiopian kale), active preparation (equals ca. 200 µmol AITC), for 5 days. Specific nutritional regimen during wash-out (7 days before intervention) and during interventio

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: healthy, non-smoker

Exclusion criteria

Exclusion criteria: chronic diseases, pregnancy, over-/underweight

Design outcomes

Primary

Measure	Time frame
Anti-genotoxicity, pre and post intervention, using the Comet assay	—

Secondary

Measure	Time frame
Parameters of oxidative stress and inflammation, pre and post intervention; modulation of telomerase activity, pre and post intervention, using the TRAP assay; traceability and absorption/excretion of bioactive substances, pre and post intervention, respectively, using LC-ESI-MS/MS.	—

Countries

Germany

Contacts

Public ContactNina Schlotz

Universitätsklinikum Freiburg, Institut für Prävention und Tumorepidemiologie, AG Molekulare Präventivmedizin

nina.schlotz@uniklinik-freiburg.de076127082240

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026