TRansabdominal Ultrasonography of the bowel in Subjects with Crohn’s disease To monitor disease activity

TRansabdominal Ultrasonography of the bowel in Subjects with Crohn’s disease To monitor disease activity - TRUST

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00010805

Enrollment

250

Registered

2016-07-07

Start date

2010-11-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K50.1

Interventions

Group 1: At all study visits (Baseline, 3, 6 and 12 months, the following bowel segments will be evaluated by US: Terminal Ileum, Cecum / ascending colon, Transverse colon, Descending colon, Sigmoid c

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with a proven diagnosis of ileocecal and / or colonic Crohn's disease and currently at least moderate disease activity (HBI = 7)

Exclusion criteria

Exclusion criteria: Patients with ileal stoma; Patients post bowel resection surgery; Patients with CD restricted to small bowel, gastroduodenal or anorectal areas; Pregnancy.

Design outcomes

Primary

Measure	Time frame
The primary endpoint is the change in one or more of selected US parameters within 12 months.	—

Secondary

Measure	Time frame
Secondary endpoint is the correlation of US changes with HBI changes.	—

Countries

Germany

Contacts

Public ContactAlexander Rössler

AbbVie Deutschland GmbH & Co. KG, Medical Development

alexander.roessler@abbvie.com015114037106

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 11, 2026