Multiple breath washout to diagnose pulmonary complications after allogenic stem cell transplantation in children and adolescents.

Multiple breath washout to diagnose pulmonary complications after allogenic stem cell transplantation in children and adolescents. - MBWSZT

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00010772

Enrollment

Registered

2016-07-27

Start date

2016-04-06

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients after hematopoietic stem cell transplantation at < 18 years for all transplantable conditions

Interventions

Group 1: Children and adolescents who are planned to undergo an allogenic stem cell transplantation are followed up prospectively with the multiple breath washout to assess lung function.

Eligibility

Sex/Gender

All

Age

6 Years to 25 Years

Inclusion criteria

Inclusion criteria: Age > 6 years, allogenic hematopoietic stem cell transplantation < 18 years of age done/planned, informed consent.

Exclusion criteria

Exclusion criteria: Age < 6 years, lack of informed consent, lack of understanding for the study, previous pulmonary disease

Design outcomes

Primary

Measure	Time frame
Early recognition of pulmonary complications (esp. bronchiolitis obliterans) in children and adolescents after HSCT with MBW compared to classic lung function tests.	—

Secondary

Measure	Time frame
Improved quality of life resulting of adapting therapy earlier in case of pulmonary complications after HSCT.	—

Countries

Germany

Contacts

Public ContactSebastian Bode

Zentrum für Kinder- und Jugendmedizin, Universitätsklinikum Freiburg

Sebastian.Bode@uniklinik-freiburg.de0761-270-43010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026