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Function of the left atrium after interventional closure of the left atrial appendage

Function of the left atrium after interventional closure of the left atrial appendage - LAA Closure - Hemodynamic Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00010768
Enrollment
150
Registered
2016-07-07
Start date
2015-05-04
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I48.1

Interventions

Group 1: Patients with an indication for an interventional atrial appendage closure and successful procedure are involved in our study after giving their informed consent. Patients undergo an Evaluati

Sponsors

Universitätsklinikum Magdeburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years; both gender; all ethnic Groups; Weight: no Limitation; women: excluded pregnancy; procedure: successful interventional closure of the left atrial appendage.

Exclusion criteria

Exclusion criteria: Patients with known coronary heart disease or instable angina pectoris, severe valvular heart disease, severe diastolic dysfunction, severe pulmonary hypertension, anaemia, acute infection with fever and increase of C reactive protein and/or leukocytosis, isolated leukocytosis, increased C reactive protein, severe renal or liver insufficiency, neoplasia, pregnancy

Design outcomes

Primary

MeasureTime frame
Primary Outcome measure is the proof of a significant Change in the neurohumoral Response to hemodynamic overload after successful closure of the left atrial appendage

Secondary

MeasureTime frame
Thrombogenesis and position of the atrial appendage closure device in the transesophageal echocardiography 45 days and 6 months after the Implantation prozedure.

Countries

Germany

Contacts

Public ContactBlerim Luani

Universitätsklinikum MagdeburgKlinik für Kardiologie und Angiologie

blerim.luani@med.ovgu.de0391 67 15 206

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 8, 2026