I48.1
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age over 18 years; both gender; all ethnic Groups; Weight: no Limitation; women: excluded pregnancy; procedure: successful interventional closure of the left atrial appendage.
Exclusion criteria
Exclusion criteria: Patients with known coronary heart disease or instable angina pectoris, severe valvular heart disease, severe diastolic dysfunction, severe pulmonary hypertension, anaemia, acute infection with fever and increase of C reactive protein and/or leukocytosis, isolated leukocytosis, increased C reactive protein, severe renal or liver insufficiency, neoplasia, pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Outcome measure is the proof of a significant Change in the neurohumoral Response to hemodynamic overload after successful closure of the left atrial appendage | — |
Secondary
| Measure | Time frame |
|---|---|
| Thrombogenesis and position of the atrial appendage closure device in the transesophageal echocardiography 45 days and 6 months after the Implantation prozedure. | — |
Countries
Germany
Contacts
Universitätsklinikum MagdeburgKlinik für Kardiologie und Angiologie