Mental symptoms F11.2
Conditions
Interventions
Group 1: Patients in OST with slow release oral morphine will be observed over a 12-months Periode with 5 Points of assessment
Sponsors
Zentrum für Interdisziplinäre Suchtforschung der Universität Hamburg (ZIS)Universitätsklinikum Hamburg-EppendorfKlinik für Psychiatrie und Psychotherapie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Opioid dependent patients (F11.2 acc. to ICD-10) - In OST with d, l-methadone or l-methadone or buprenorphine (including buprenorphine/naloxone) or diamorphine - Unsatisfactory substitution treatment with d, l-methadone or l-methadone or buprenorphine or diamorphine in mental or physical dimensions (e.g. ongoing craving for heroin, intolerable side effects) - Willingness to switch from former substitution agent to SROM - Capable of following the treatment and answering the questionnaires - Informed consent.
Exclusion criteria
Exclusion criteria: - According to SmPC (hypersensitivity to the active or one of the other constituents, Ileus, acute abdomen) - Patients currently treated with SROM (Substitol®).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mental symptoms (GSI of Brief Symptom Inventory-18), comparison between baseline and month 12 | — |
Secondary
| Measure | Time frame |
|---|---|
| Retention rate at 3, 6 and 12 months, Concomitant drug use, Physical health, Quality of Life, Craving for Heroin, Satisfaction with treatment | — |
Countries
Germany
Contacts
Public ContactUwe Verthein
Zentrum für Interdisziplinäre Suchtforschung der Universität Hamburg (ZIS), Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Psychiatrie und Psychotherapie
Outcome results
None listed