Clinical long-term outcome and MRI results of scaffold-assisted autologous chondrocyte implantation for focal articular cartilage defects in the knee joint

Clinical long-term outcome and MRI results of scaffold-assisted autologous chondrocyte implantation for focal articular cartilage defects in the knee joint - BSC-12J-FU

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00010658

Enrollment

Registered

2016-06-15

Start date

2013-09-23

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M94.96

Interventions

Group 1: Between 2001 and 2003, 76 patients received BioSeed-C as a matrix for autologous chondrocyte implantation. 12 years later, the patients are now asked to describe their current symptoms by dif

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 18 to 65-year old patients with focal articular cartilage defects outerbridge grade III-IV located on femur condyles, trochlea and patella with a defect size >2x2cm, that have been treated with BioSeed-C in the Freiburg University Hospital between 2001 and 2003

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Assessment of clinical outcome and function by the Knee injury and Osteoarthritis Outcome Score (KOOS) at the time of examination	—

Secondary

Measure	Time frame
Improvement of pain and quality of life (International Knee Documentation Committee Score (IKDC), Lysholm, Noyes, Henderson-Kreuz scoring system)	—

Countries

Germany

Contacts

Public ContactRichard Kalkreuth

Uniklinik FreiburgDepartment Orthopädie Traumatologie

richard.kalkreuth@uniklinik-freiburg.de076136308957

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026