only healthy children will be investigated healthy volunteers
Conditions
Interventions
Group 1: All children will be tested with
1) structural MRI
2) functional MRI language parpadigm
3) diffusion weighted MRI
4) neurolinguistic testing
Sponsors
Medizinische Universität Wien
Eligibility
Sex/Gender
All
Age
6 Years to 16 Years
Inclusion criteria
Inclusion criteria: an age of = 6 and = 16 normal neurological findings in fetal MRI and ultrasound both parents native German speakers good language comprehension and ability to follow instructions intact vision and hearing
Exclusion criteria
Exclusion criteria: twin or multiple pregnancy history of neurological or psychiatric disease general MR contraindication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The queries regarding primary and secondary outcome do not apply to the present study. I the following, we specify the objectives of the study: 1) a positive correlation between prebirth structural lateralization of the planum temporale and childhood functional lateralization of language. 2) a positive correlation between prenatal structural asymmetry of the planum temporale and lateralization of language-related white matter bundles in childhood. 3) a correlation between prenatal anatomical asymmetry of the planum temporale and later language abilities, with a prenatal leftward asymmetry of the planum temporale significantly associated with better language abilities. 4) distributed markers beyond the asymmetry of the planum temporale that predict language functioning. | — |
Secondary
| Measure | Time frame |
|---|---|
| The queries regarding primary and secondary outcome do not apply to this basic research of healthy children. | — |
Countries
Austria
Contacts
Public ContactLisa Bartha-Doering
Universitätsklinik für Kinder- und JugendheilkundeMedizinische Universität Wien
Outcome results
None listed