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The influence of dental prophylaxis intervention on the risk of bacteremia in children with renal insufficiency.

The influence of dental prophylaxis intervention on the risk of bacteremia in children with renal insufficiency.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00010580
Enrollment
90
Registered
2016-07-11
Start date
2016-07-11
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prophylaxis of gingivitis Reduction of bacteremia after tooth brushing and reduction of pro-inflammatory mediators

Interventions

Group 1: Clinical trial, interventional study with a form of waiting-group design: Testgroup will receive a demand orientated oral intensive prophylaxis. 1. step: professional toothcleaning and oral h

Sponsors

Universitätsklinikum KölnZMMKAbteilung für Zahnerhaltung und Parodontologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 25 Years

Inclusion criteria

Inclusion criteria: - Patients with a known renal insufficiency (stage III-V and after transplantation) - Patients with chronic renal insufficieny at the age of 6 to 25 years. - Patients with a higher risk of gingivitis (GI > 0; PSI stage 0-2) - Patients, who did not take antibiotics for the last 2 weeks - Patients who agreed the consent form written and verbal - Patients who do not participate in a different clinical trial

Exclusion criteria

Exclusion criteria: - Patients who do not have suitable conditions for a dental treatment - Patients who regulary have to take antibiotics

Design outcomes

Primary

MeasureTime frame
Free of Gingivitis, measured by papilla bleeding index

Secondary

MeasureTime frame
A reduction of pro-inflammatory Mediators and risk of bacteremia

Countries

Germany

Contacts

Public ContactKarolin Höfer

Universitätsklinikum KölnZMMKAbteilung für Zahnerhaltung und Parodontologie

karolin.hoefer@uk-koeln.de0221 478 96743

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 8, 2026