Early diagnosis and Treatment of acute kidney injury

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

DRKS

Registry ID

DRKS00010530

Enrollment

100

Registered

2016-05-18

Start date

2015-11-24

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N17.9

Interventions

Group 1: patients with acute kidney injury and usual care, Nephrology referral may be requested Group 2: intensified care, all patients with acute kidney injury (AKI) receive Nephrology referral, for

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients treated at non-Nephrology normal wards with acute kidney injury, ability for health judgement

Exclusion criteria

Exclusion criteria: -chronic dialysis or Organ transplantation, patients on renal wards, patients on ICU, <18 years, infaust prognosis

Design outcomes

Primary

Measure	Time frame
Renal recovery (Proportions of patients, mL/min) according to recommendations by the KDIGO Initiative (serum creatinine, proteinuria) at hospital discharge	—

Secondary

Measure	Time frame
1.) Patient-related: -proportions of patients with renal recovery at day 90 after AKI (Acute Kidney Injury), eGFR-loss(ml/min) at day 90 after AKI; AKI-severity and -duration, Proportion of patients with AKI-progression (Stage 1->2, 1->3, 2->3), de-novo or or progression of chronic kidney disease at Hospital discharge and at day 90 after AKI (Change of CKD stage, eGFR loss, novel proteinuria, increase of known proteinuria), proportions of patients with: renal acidosis, hyperkalemia, (lung)oedema, iv diuretics for Treatment of hypervolemia, length of stay ICU-/hospital, Proportion of patients with re-hospitalization (AKI as cause?), Proportion of patients with renal replacement therapy, renal replacement therapy-free days at 90 days after AKI, Letality (hospital/at day 90 after AKI), Patient-reported Quality of life (short form health questionnaire) 2.) Process-related: - diagnostic delay: from AKI-diagnosis until AKI-Documentation in Patient Chart or induction of Treatment, therapeutic delay: from AKI-Diagnosis until und induction of treatment, state of care, Proportion of diagnostic/therapeutic measures, documentation of AKI and other kidney-related diagnoses in patients Chart/discharge letter, frequency of kidney function measurement, e.g. Serum creatinine, estimation of treatment/documentation effort	—

Measure

Time frame

1.) Patient-related: -proportions of patients with renal recovery at day 90 after AKI (Acute Kidney Injury), eGFR-loss(ml/min) at day 90 after AKI; AKI-severity and -duration, Proportion of patients with AKI-progression (Stage 1->2, 1->3, 2->3), de-novo or or progression of chronic kidney disease at Hospital discharge and at day 90 after AKI (Change of CKD stage, eGFR loss, novel proteinuria, increase of known proteinuria), proportions of patients with: renal acidosis, hyperkalemia, (lung)oedema, iv diuretics for Treatment of hypervolemia, length of stay ICU-/hospital, Proportion of patients with re-hospitalization (AKI as cause?), Proportion of patients with renal replacement therapy, renal replacement therapy-free days at 90 days after AKI, Letality (hospital/at day 90 after AKI), Patient-reported Quality of life (short form health questionnaire) 2.) Process-related: - diagnostic delay: from AKI-diagnosis until AKI-Documentation in Patient Chart or induction of Treatment, therapeutic delay: from AKI-Diagnosis until und induction of treatment, state of care, Proportion of diagnostic/therapeutic measures, documentation of AKI and other kidney-related diagnoses in patients Chart/discharge letter, frequency of kidney function measurement, e.g. Serum creatinine, estimation of treatment/documentation effort

—

Countries

Germany

Contacts

Public ContactMichael Haase

KfH Nierenzentrum Magdeburg

michael.haase@med.ovgu.de0331-2806911

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 27, 2026