Effect of the FTO-genotypes on the differences in energy expenditure after cold exposure The "FREECE" study

Effect of the FTO-genotypes on the differences in energy expenditure after cold exposure The "FREECE" study - FREECE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00010489

Enrollment

120

Registered

2016-09-22

Start date

2016-10-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy subjects

Interventions

Group 1: 3 days before measurement, subjects have to fill out a dietary protol that records all meals an beverages consumed on that three days. 24 hours before measurement, subjects are not allowed t

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: healthy volunteers, BMI >18,5 kg/m^2

Exclusion criteria

Exclusion criteria: smokers, pregnant and lactating women, chronic diseases, cardiovascular diseases, Type 2 diabetes

Design outcomes

Primary

Measure	Time frame
Primary aim of the study is the cold induced energy expenditure (measured by indirect calorimetry) and the expression of "browning" biomarkers in white adipose tissue (fat biopsy) and possible correlations with the FTO-locus	—

Secondary

Measure	Time frame
Secondary aim of the study are circulating "browning" bio markers and the composition of the microbiome.	—

Countries

Germany

Contacts

Public ContactClaudine Seeliger

Else Kröner-Fresenius-Zentrum für Ernährungsmedizin der TU München

claudine.seeliger@tum.de08161712006

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026