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CAD/CAM vs. conventional minimal invasive therapeutic intervention of severe non carious lesions: Clinical performance and quality of life improvement.

CAD/CAM vs. conventional minimal invasive therapeutic intervention of severe non carious lesions: Clinical performance and quality of life improvement. - MINERVA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00010476
Enrollment
96
Registered
2018-04-03
Start date
2018-04-20
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe non-carious lesions K03.2

Interventions

Group 1: CAD/CAM rehabilitation: minimal invasive CAD/CAM full-coverage crowns or veneers and defect-oriented posterior onlay restorations. Group 2: Conventional all-ceramic rehabilitation: ,inimal in

Sponsors

Heinrich-Heine-Universität Düsseldorf
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Extensive erosive defects (BEWE Index 14-18 = necessity of a full-mouth rehabilitation; n = 14-28 teeth/patient) due to exogenous (acidic drinks) or endogenous factors (GERD or eating disorders), with severe loss of the vertical dimension of occlusion, hypersensitivity, reduced chewing ability, impaired aesthetics.

Exclusion criteria

Exclusion criteria: A history of alcohol or drug abuse, missing teeth, poor oral hygiene, pronounced parafunctions, with allergies to any of the applied materials or with life-threatening severe general diseases.

Design outcomes

Primary

MeasureTime frame
The primary endpoint is defined on an individual tooth-level as time from tooth restoration to failure, where failure is defined as the combined endpoint of restoration fracture, secondary caries, debonding, marginal discoloration, degradation of surface structure and anatomic form.

Secondary

MeasureTime frame
Success 3 years after treatment. Quality of dental restorations (USPHS criteria). Patient’s centred satisfaction. Safety.

Countries

Germany

Contacts

Public ContactPetra Gierthmuehlen

Universitätsklinikum Düsseldorf Poliklinik für Zahnärztliche Prothetik

Petra.Gierthmuehlen@med.uni-duesseldorf.de0211- 8 11 81 42

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026