E66
Conditions
Interventions
dose: 3g per day (per os) for 12 weeks
Group 2: Placebo - capsule containing 0,5 g of sunflower oil
Sponsors
Department of Pediatric Gastroenterology and Metabolic DiseasesPoznan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Female sex 2. Age greater than 18 years 3. Body mass index (BMI) = 25 kg/m2
Exclusion criteria
Exclusion criteria: 1. A history of chronic systemic disease (with the exception of hypertension). 2. Celiac disease. 3. Type 2 diabetes. 4. Pancreatic and/or liver diseas. 5. Current or recent (within the preceding month) treatment with CLA or agents interfering with fat digestion and/or absorption (chitosan, orlistat, green tea) 6. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Starch and lipid digestion assessed by a starch breath test and a mixed triglyceride breath test at study begin and after twelve weeks of nutritional intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight, body composition(assessed by dual-energy X-ray absorptiometry (DXA), total energy expenditure (assessed by 13C bicarbonate sodium breath test), liver metabolism (assessed by 13C methacetin breath test), mineral status (assessed in 24-hour urine collection and in hair samples), blood lipid profile, polyunsaturated fatty acids blood profile; all secondary outcomes were measured at the study begin and after nutritional intervention | — |
Countries
Poland
Contacts
Public ContactJaroslaw Walkowiak
Department of Pediatric Gastroenterology and Metabolic DiseasesPoznan University of Medical Sciences
Outcome results
None listed