Hypoxia related metabolism of the brain

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00010452

Enrollment

Registered

2016-05-04

Start date

2007-07-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Only healthy volunteers were included. E11

Interventions

Group 1: Condition of hypoxia by stepwise reduction of inspiratory oxygen-content down to 11 vol%. (overall 40 min). During the whole experiment: Blood-collections to examine-glucose-metabolism (gluc

140

200

210

220: 230

280

320

360 min. Group 2: Condition of placebo. Identical conditions like arm 1. But no oxygen reduction.

Eligibility

Sex/Gender

Male

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Normal state of health

Exclusion criteria

Exclusion criteria: Medication, acut or chronic diseases, shift-work

Design outcomes

Primary

Measure	Time frame
Changes in circulation parameters, capnometry, blood pressure, pulse oxymetry. During hypoxia-state: Every 5 minutes.	—

Secondary

Measure	Time frame
Changes in hormone levels by blood collections (Time-points: -15; 90; 140; 200; 210; 220: 230; 280; 320; 360 min) Measurements of glucose tolerance by CLAMP-experiment (overall 360 min).	—

Countries

Germany

Contacts

Public ContactJan Christian Martens

Universität zu LübeckSektion für Psychoenurobiologie

martens@pnb.uni-luebeck.de+49 451 3101 7539

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026