Healthy Subjects
Conditions
Interventions
Group 1: This study compares 2 interventions within one group:
Intervention A: High-stress task.
Using an established MRI modified version of the Trier Social Stress Test (TSST) participants solve h
Sponsors
Sektion für PsychoneurobiologieUniversität zu Lübeck
Eligibility
Sex/Gender
Male
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Body Mass Index 20 - 25kg / qm
Exclusion criteria
Exclusion criteria: acute/chronic internal, neurologic or psychiatric diseases, alcohol- or nicotinabusus (> 5 cigarettes/d), medication, excessive and competitive sports (z.B. marathon) and extraordinary psychiological and physical stress situations; general exclusion criteria for MRT-Investigations: metal implants, pacemakers, artificial joints or heart valves, surgical clips, bone screws or plates, pivot teeth, piercing, large colored tattoos, gunshot wounds, severe claustrophobia); Body mass index > 25 kg / qm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Using 31-phosphorus magnetic resonance spectroscopy changes in cerebral energy metabolites adenosine triphosphate (ATP) and phosphocreatine (PCr) (3.0 Tesla) were recorded in the magnetic resonance imaging scanner before, while and after stress intervention as well as before while and after no-stress condition. | — |
Secondary
| Measure | Time frame |
|---|---|
| The success of the stress intervention is controlled by determining the following blood parameters: ACTH, cortisol, epinephrine and norepinephrine. In addition, the peripheral glucose, insulin and C-peptide are determined. The change in food intake is recorded using standardized established ad libitum buffet. | — |
Countries
Germany
Contacts
Public ContactAlina Kistenmacher
Sektion für PsychoneurobiologieUniversität zu Lübeck
Outcome results
None listed