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Influence of AQP5 (-1364 A/C) promoter polymorphism on immune cell migration and sepsis lethality

Influence of AQP5 (-1364 A/C) promoter polymorphism on immune cell migration and sepsis lethality

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00010437
Enrollment
160
Registered
2016-04-26
Start date
2011-01-10
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blood poisoning A41.9 R57.2

Interventions

Group 1: Outcome of severe sepsis is estimated in patients with Septic Shock patients, which were genotyped to be A-allele carriers. Blood collection was performed for diagnosis, cytokine measurement

Sponsors

Universitätsklinikum Essen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: septic shock

Exclusion criteria

Exclusion criteria: age below 18, no consent, non-european ethnicity

Design outcomes

Primary

MeasureTime frame
30-day lethality

Countries

Germany

Contacts

Public ContactKatharina Rump

Ruhr Universität BochumKnappschaftskrankenhaus BochumKlinik für Anästesiologie

katharina.k.rump@rub.de02343229242

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 11, 2026