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Randomized controlled trial on Pringle Maneuver to reduce blood loss during Stapler Hepatectomy - PriMal StHep

Randomized controlled trial on Pringle Maneuver to reduce blood loss during Stapler Hepatectomy - PriMal StHep - PriMal StHep

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00010427
Enrollment
106
Registered
2016-04-21
Start date
2016-06-02
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C22.0 C78.7 C22.1 C22.3 C22.4 C22.2 C22.7 C22.9 D13.4

Interventions

Group 1: Depending on the planned procedure, an upper midline incision with or without right lateral extension (“reversed L – shape”) is performed in a regular dorsal position. After the hepatic lesio
30(3):419–30). In all cases the central venous pressure will be kept at 5 mmHg or below by the anaesthesiologists according to routine liver surgery standards. Group 2: Depending on the planned proce
30(3):419–30). In all cases the central venous pressure will be kept at 5 mmHg or below by the anaesthesiologists according to routine liver surgery standards.

Sponsors

Universitätsklinikum HeidelbergKlinik für Allgemein-, Viszeral- und Transplantationschirurgie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1)Patients undergoing Hemihepatectomy 2)Age eighteen or older 3)written informed consent for participation in the trial

Exclusion criteria

Exclusion criteria: 1)Anatomical alterations rendering study treatment impossible 2)Situation post interventional or operative portal vein embolization or ligation 3)Simultaneous resection of other organs excluding the gall bladder and the common bile duct 4)Liver cirrhosis exceeding "Child Pugh A"

Design outcomes

Primary

MeasureTime frame
Total intraoperative Blood loss during Stapler Hemihepatectomy

Secondary

MeasureTime frame
•Intraoperative BL per resection plane size (ml/cm²) •Intraoperative blood transfusion requirements •Postoperative ALT levels day 1 and 3 •Postoperative total Bilirubin levels day 1 and 3 •Postoperative INR day 1 and 3 •Blood transfusion requirements within the first three postoperative days •90 – days Mortality

Countries

Germany

Contacts

Public ContactPeter Schemmer

Universitätsklinikum HeidelbergKlinik für Allgemein-, Viszeral- und Transplantationschirurgie

peter.schemmer@med.uni-heidelberg.de06221566111

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 2, 2026