G81.1 I63.9
Conditions
Interventions
Group 1: - Casting for 14 days
- BoNT injection on day 14 (at time of 0)
Group 2: - Simultaneous casting and injection of BoNT at the time of 0
Group 3: - BoNT injection at time of 0
- 14 days later (
Sponsors
Neurologisches Rehabilitationszentrum Leipzig
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Aged 18 years - stoke with spasticity of the upper limb -MAS 2 - 3 - noticeable "catch" (according to Tardieu Scale) -pROM wrist affected: = 0 ° in extension
Exclusion criteria
Exclusion criteria: - Age 3 - wrist is not up to the 0 position (PROM) mobilized - no meaningful "catch" (Tardieu Scale) - fixed contracture of the fingers and / or wrist - Serious additional diseases - severe communication disorder - myasthenia gravis, Lambert-Eaton syndrome, ALS or other serious neuromuscular diseases - severe dysphagia - current administration of aminoglycosides - proven hypersensitivity to Clostridium botulinum toxin A or any of the excipients of the preparation Dysport® - Planned operations within the next 12 weeks ago - pregnancy, lactation period - anticoagulant therapy (Warfarin, Falithrom) - infections in the injection area and skin damage in the area of ??castings - Significant edematous swelling of the arm and hand - Peri-articular heterotrophic ossification in the investigation area - Unstable fractures in the study area - gout and diseases of rheumatic at the involved joints (upper limb)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified ashworth scale (MAS) modified tardieu scale | — |
Secondary
| Measure | Time frame |
|---|---|
| - Active and passive range of motion (ROM or PROM) - dorsiflexion force - grip strength - Wolf Motor Function Test (WMFT), optional ARAT | — |
Countries
Germany
Contacts
Public ContactHartwig Woldag
Neurologisches Rehabilitationszentrum Leipzig
Outcome results
None listed