calcium and magnesium undersupply E61.2 E58
Conditions
Interventions
Group 1: Total study period takes 9 resp. 10 weeks. At five resp. six examination days (with a break of one week), the participants (20 persons per study arm) get energy-adjusted, low-calcium and low-
Sponsors
Gesellschaft der Freunde und Förderer der deutschen Mineralbrunnenindustrie e.V.
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: competent men and women aged 18-50 years; BMI range between 18,5-29,9 kg/m²; Ability and willingness of study participants to follow study leaders instructions (Compliance to study procedure, intake of study products according to intake recommendations, etc.), written consent after information about study contents, procedure and risks
Exclusion criteria
Exclusion criteria: allergies regarding study product contents; intake of dietary supplements and / or drugs containing calcium or / and magnesium during study phase; severe chronic illness (Diabetes mellitus Typ I, kidney diseases, liver diseases, manifested coronary diseases, cancer); coagulation dysfunctions as well as intake of anticoagulating drugs e.g. Marcumar (exeptional case: ASS); chronic gastrointestinal diseases (colitis ulcerosa, morbus crohn, pancreas insufficiency); regularly intake of laxative medicines; pregnancy or lactation; addiction to alcohol and/or drugs; missing consent or refusing / reset of the consent; participation in another clinical study at the same time or within past 30 days; planned surgery within the next 3 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Calcium (blood parameter) at time 1 hour after beginning, 2 hours after beginning, 3 hours after beginning, 4 hours after beginning, 5 hours after beginning, 6 hours after beginning, 8 hours after beginning, 10 hours after beginning; Magnesium (blood parameter) at time 1 hour after beginning, 2 hours after beginning, 3 hours after beginning, 4 hours after beginning, 5 hours after beginning, 6 hours after beginning, 8 hours after beginning, 10 hours after beginning | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary calcium at time 0 (start measurement), 0-2 hours after beginning, 2-4 hours after beginning, 4-6 hours after beginning, 6-8 hours after beginning, 8-12 hours after beginning, 12-24 hours after beginning; Urinary magnesium at time at time 0 (start measurement), 0-2 hours after beginning, 2-4 hours after beginning, 4-6 hours after beginning, 6-8 hours after beginning, 8-12 hours after beginning, 12-24 hours after beginning | — |
Countries
Germany
Contacts
Public ContactTheresa Greupner
Institut für Lebensmittelwissenschaft und Humanernährung
Outcome results
None listed