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Ischemic preconditioning in the surgical treatment of brain tumors

Ischemic preconditioning in the surgical treatment of brain tumors - RIP_BT_RCT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00010409
Enrollment
60
Registered
2016-10-13
Start date
2015-09-02
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative ischemia in patients with brain tumors C71.9 C79.3 I63.9

Interventions

Group 1: A blood pressure cuff is attached to the arm (contralateral to the brain tumor) and inflated three times for 5 minutes at 200 mmHg in the treatment group after induction of anesthesia. Betwe

Sponsors

Neurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with suspected primary or metastatic brain tumor for which surgical resection is planned; Consent to participate in the study; Age> 18.

Exclusion criteria

Exclusion criteria: Non OP-enabled patient (from anesthesiological, medical or surgical view); Patients who have to be operated immediately without extensive preoperative diagnosis; Lack of surgical consent; Lack of consent to participate in the study; Pregnancy; Age <18 years; History of peripheral arterial disease (PAD) or DM with use of oral antidiabetics.

Design outcomes

Primary

MeasureTime frame
Presence of postoperative ischemia validated with early postoperative cMRI (<72h)

Secondary

MeasureTime frame
Volume of Ischemia (cMRT <72h). New postoperative (1 week) deficit. Clinical status assessed by KPS (1 week postoperative).

Countries

Germany

Contacts

Public ContactJens Gempt

Neurochirurgische Klinik und Poliklinik, Klinikum rechts der Isar

jens.gempt@tum.de08941409722

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 9, 2026