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Retrospective evaluation of prolongation of preeclamptic pregnancies by lipidapheresis with H.E.L.P.-apheresis compared to a control group

Retrospective evaluation of prolongation of preeclamptic pregnancies by lipidapheresis with H.E.L.P.-apheresis compared to a control group

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00010235
Enrollment
30
Registered
2017-05-24
Start date
2016-05-04
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

O14.9

Interventions

Group 1: Already finished study "Prolongation of pregnacies with preeclampsie by lipid apheresis" (DRKS00004527
EK Nr 475/12): Patients with preeclampsia were treated with lipidapheresis until delivery due to maternal or fetal condition was necessary. Group 2: historical, retrospektive controls not treated with

Sponsors

Universitätsklinikum Freiburg Institut für Klinische Chemie und Laboratoriumsmedizin
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Pregnant patients with preeclampsia in early pregnancy (before 32th week of pregnancy) according to the following criteria of the German society of obstetrics and gynecology (August 2010): Blood pressure over 140/90 mmHg and proteinuria (> 300 mg/24h or positive urine dipstick test), with or without intrauterine growth retardation, pathological dopplersound evaluation.

Exclusion criteria

Exclusion criteria: Younger than 18 years. Emergency delivery after admission. Other diseases/events that can cause emergency delivery.

Design outcomes

Primary

MeasureTime frame
Prolongation of pregnancies in days. Duration from admission to delivery.

Secondary

MeasureTime frame
Clinical data from pregnant women and children: clinical situation, weight, blood pressure, laboratory parameters (thrombocytes, total protein, haptoglobin, creatinin, GOT, GPT, proteinuria). Ultrasound data (amniotic fluid,...). Newborn: weight, pH of cord blood, APGAR, clinical situation

Countries

Germany

Contacts

Public ContactChristine Contini

Universitätsklinikum FreiburgInstitut für Klinische Chemie und Laboratoriumsmedizin

christine.contini@uniklinik-freiburg.de+49 761 270 73120

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026