Hemophilia D66 D67
Conditions
Interventions
Group 1: Patients with inherited Hemophilia A or B aged older than 60 years will be asked for different clinical parameters at study start and annually for further 5 years. (bleeding frequency and ble
Sponsors
Goethe-Universität Frankfurt
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: ? aged older than 60 years ? confirmed diagnosis of hemophilia A or B ? informed consent signed
Exclusion criteria
Exclusion criteria: ? younger than 60 years ? no confirmed diagnosis of hemophilia A or B ? no informed consent ? lack of comprehension of study documents
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding rate and bleeding pattern in the preceding year , duration and kind of Substitution therapy, data collection by CRF at study start and annually | — |
Secondary
| Measure | Time frame |
|---|---|
| Interaction of clinical, emotional and functional parameters as well as influence of age, Co-morbidities and medication; Annual data collection by CRF and validated questionnaires (German Versions): Clinical: ? Joint Condition (Hemophilia Joint Health Score, HJHS) ? Co-Morbidity and Co-Medication ? Cause and duration of hospitalization ? Level of care ? death/Cause of death Emotional: ? Depression (Geriatric depressions scale questionnaire, GDS-15) ? Health-related quality of life: SF-36v2 (© QualityMetric Incorporated, USA, 2006) Functional: ? physical functionality: Haemophilia Activity List 2.0 2015 ? Tinetti Motility Test (Balance & Gait) Comparison of Co-Morbidity with normal population (aggregated Data of RKI) | — |
Countries
Germany, Switzerland
Contacts
Public ContactWolfgang Miesbach
Hämophiliezentrum/Hämostaseologie
Outcome results
None listed